Dr. Mattson is considered a leader in the area of cellular and molecular mechanisms underlying neuronal plasticity and neurodegenerative disorders, and has made major contributions to understanding the pathogenesis of Alzheimer¡¦s disease, Parkinson¡¦s disease, amyotrophic lateral sclerosis and stroke, and to their prevention and treatment. He has published more than 400 original research articles and numerous review articles in leading journals and books, and has edited 8 books in the areas of neuronal signal transduction, neurodegenerative disorders and mechanisms of aging.

Dr. Mattson has received many awards including the Metropolitan Life Foundation Medical Research Award, the Alzheimer¡¦s Association Zenith Award, the Jordi Folch Pi Award, the Santiago Grisolia Chair Prize, and several Grass Lectureship Awards. He is Editor-in-Chief of NeuroMolecular Medicine and Aging Research Reviews, and is a Managing or Associate Editor of the Journal of Neuroscience, Trends in Neurosciences, the Journal of Neurochemistry, the Neurobiology of Aging, and the Journal of Neuroscience Research.

He has served on several NIH study sections and on scientific advisory boards for many research foundations. He has trained more than 40 postdoctoral and predoctoral scientists, and has made major contributions to the education of undergraduate, graduate and medical students.

Mattson MP, Murrain M, Guthrie PB, Kater SB. Fibroblast growth factor and glutamate: opposing roles in the generation and degeneration of hippocampal neuroarchitecture. J Neurosci. 1989 Nov;9(11):3728-40.
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Mattson MP. Antigenic changes similar to those seen in neurofibrillary tangles are elicited by glutamate and Ca2+ influx in cultured hippocampal neurons.
Neuron. 1990 Jan;4(1):105-17.
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Mattson MP, Rychlik B, Chu C, Christakos S. Evidence for calcium-reducing and excito-protective roles for the calcium-binding protein calbindin-D28k in cultured hippocampal neurons. Neuron. 1991 Jan;6(1):41-51.
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Cheng B, Mattson MP. NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis. Neuron. 1991 Dec;7(6):1031-41.
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Mattson MP, Cheng B, Davis D, Bryant K, Lieberburg I, Rydel RE. beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci. 1992 Feb;12(2):376-89.
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Mattson MP, Cheng B, Culwell AR, Esch FS, Lieberburg I, Rydel RE. Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein. Neuron. 1993 Feb;10(2):243-54.
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Cheng B, Christakos S, Mattson MP. Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis. Neuron. 1994 Jan;12(1):139-53.
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Mark RJ, Hensley K, Butterfield DA, Mattson MP. Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death. J Neurosci. 1995 Sep;15(9):6239-49.
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Barger SW, Horster D, Furukawa K, Goodman Y, Krieglstein J, Mattson MP. Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation. Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9328-32.
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Furukawa K, Barger SW, Blalock EM, Mattson MP. Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein. Nature. 1996 Jan 4;379(6560):74-8.
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